Blind use of external medicine for hand vitiligo will only aggravate the patient's condition and cause the recurrence of persistent vitiligo. Some patients with vitiligo are anxious to treat the disease. Once they see a little effect of topical medication, they will be mentally dependent on topical medication, and will often increase the dosage and frequency of use, but long-term use will lead to drug resistance and drug resistance. , Burns the skin and affects the treatment of later illnesses.