Dr.Wang Jiangmei from Huahai Vitiligo Hospital shared: Is epidermal cell transplantation effective i

Date:2020-07-19 Hit:82


Vitiligo is a disfiguring disease. Although it is not painful or itchy, it brings great pain to people's body and mind. Its treatment methods and efficacy are also more concerned by patients and friends. Today, Huahai Vitiligo Hospital is here to share with you a common vitiligo treatment technique-epidermal cell transplantation to treat vitiligo, then how effective is it?

1. First, let's understand how leukoplakia occurs?

Human skin is composed of three layers of epidermis, dermis, and subcutaneous tissue from the outside to the inside. It is the melanin content in the epidermis that determines the human skin color, and melanin is produced by melanocytes located in the basal layer of the epidermis. When a certain pathogenic factor causes the melanocytes in the epidermis to be destroyed or dysfunction can not produce melanin, the melanin content in the epidermis will decrease or even disappear, thus forming white spots visible to the naked eye.

2. Where does melanin come from? 

The purpose of the treatment of vitiligo is to regain normal melanocytes that can produce melanin in the white spots. There are usually three sources of melanin:

1. It migrates from the melanocyte reservoir in the outer root sheath of the skin hair follicle;

2. Migrating from the melanocytes in the normal epidermis at the edge of the leukoplakia;

3. From other parts through epidermal cell transplantation.

3. What is epidermal cell transplantation? What are its advantages?

Epidermal cell transplantation to treat vitiligo uses the principle of negative pressure suction to transplant the skin epidermis from the normal part of the body to the leukoplakia lesion area to increase the number of melanocytes in the lesion area.

The traditional treatment of vitiligo includes internal medicine, external medicine, and phototherapy. The treatment time is relatively long, which can easily cause anxiety and even give up halfway. Epidermal cell transplantation for the treatment of vitiligo has the characteristics of simple operation, less patient pain, less injury, no side effects, shorter cure time, and high cure rate. It is currently one of the most effective methods for the treatment of vitiligo.

4. What are the precautions for epidermal cell transplantation?

1. Epidermal cell transplantation to treat vitiligo is suitable for patients with small lesions and stable conditions;

2. It is forbidden for patients whose disease is related to trauma, has homomorphic reaction and whose condition is in advanced stage;

3. Patients suffering from diabetes, peripheral neuritis, scar constitution and other diseases are not suitable for this type of treatment.

4. After the operation, there may be obvious pigmentation in the donor area and recipient area during the recovery process, which is darker than normal skin. After a period of time, most patients will gradually reduce the pigmentation.

5. Due to individual differences, the survival rate of epidermal cell transplantation cannot reach 100%;

However, in general, the effect of epidermal cell transplantation in the treatment of vitiligo is completely certain, especially for segmental vitiligo, which is one of the most effective treatments.

 



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